[2,6-Dichloro-4-(trifluoromethyl)phenyl]hydrazine → HCID 13630541、化合物

HRID 65383

反応式

HRID 65383 の反応式
[Cl:1][C:2]1[CH:7]=[C:6]([C:8]([F:11])([F:10])[F:9])[CH:5]=[C:4]([Cl:12])[C:3]=1[NH:13][NH2:14].Cl.C[N:17](C)[CH:18]=[C:19]([N:22]1[CH:26]=[N:25][CH:24]=[N:23]1)[C:20]#N>C(O)C>[NH2:17][C:18]1[N:13]([C:3]2[C:2]([Cl:1])=[CH:7][C:6]([C:8]([F:9])([F:11])[F:10])=[CH:5][C:4]=2[Cl:12])[N:14]=[CH:20][C:19]=1[N:22]1[CH:26]=[N:25][CH:24]=[N:23]1

参加物

4

反応物 2

HCID 688223[2,6-Dichloro-4-(trifluoromethyl)phenyl]hydrazineHCID 704142303-Dimethylamino-2-(1,2,4-triazol-1-yl)-acrylonitrile hydrochloride

生成物 1

HCID 13630541HCID 13630541、化合物収率 96%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

19 g (0.075 mole) of 2,6-dichloro-4-trifluoromethyl-phenylhydrazine and 16 g (0.075 mole) of 3-dimethylamino-2-(1,2,4-triazol-1-yl)-acrylonitrile hydrochloride in 200 ml of ethanol are heated at 75° C. to 78° C. for 5 hours, with stirring. For working up, the solvent is distilled off and the residue is triturated with water and dried over clay. 26 g (96% of theory) of 5-amino-1-(2,6-dichloro-4-trifluoromethylphenyl)-4-(1,2,4-triazol-1-yl)-pyrazole of melting point 170°-174° C. are obtained.

後処理

  1. distillationthe solvent is distilled off
  2. customthe residue is triturated with water
  3. customdried over clay

出典と根拠

ORDレコード
ord-c0666b772a7448dcacf8378d965f86b1
出典データセット
uspto-grants-1986_09
特許番号
US04614534

関連ノート

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