関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | 4-Chloro-3-nitroaniline | HCID 12477 | — |
| 反応物 | Benzene sulphochloride | HCID 22564087 | — |
| 溶媒 | Pyridine | HCID 1049 | — |
| 生成物 | N-(4-chloro-3-nitrophenyl)benzenesulfonamide | HCID 779563 | — |
反応手順
172.5 g (1 mol) of 4-amino-1-chloro-2-nitro-benzene are dissolved in 400 ml pyridine with heating. 193 g (1.09 mol) of benzene sulfochloride are slowly added dropwise, followed by heating for 1 hour at 120° C. (bath temperature). Subsequently, the solution is cast onto ice, and the 1-chloro-2-nitro-4-benzene-sulfonamido-benzene is evacuated in a vacuum. The compound is recrystallized from ethanol/water.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05132461 |
|---|
| 出典データセット | uspto-grants-1992_07 |
|---|
| ORD ID | ord-95a47984e372496c92373e91e9a338ae |
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| 出典メモ | uspto-grants-1992_07 |
|---|
