3-Chloro-1-propyne → 2,3,5,6-Tetrafluoro-4-(2-propyn-1-yl)benzyl Alcohol

反応式

Br[C:2]1[C:15]([F:16])=[C:14]([F:17])[C:5]([CH2:6][O:7]C2CCCCO2)=[C:4]([F:18])[C:3]=1[F:19].[CH2:20](Cl)[C:21]#[CH:22]>>[CH2:22]([C:2]1[C:3]([F:19])=[C:4]([F:18])[C:5]([CH2:6][OH:7])=[C:14]([F:17])[C:15]=1[F:16])[C:21]#[CH:20]

参加物

反応物 2

HCID 122213-Chloro-1-propyne

HCID 136705722-[(4-Bromo-2,3,5,6-tetrafluorophenyl)methoxy]tetrahydro-2H-pyran

生成物 1

HCID 114359092,3,5,6-Tetrafluoro-4-(2-propyn-1-yl)benzyl Alcohol

実験手順

4-(Prop-2-yn-1-yl)-2,3,5,6-tetrafluorobenzyl alcohol was prepared from 2-[4-bromo-2,3,5,6-tetrafluorobenzyloxy)-tetrahydropyran and propargyl chloride, by a two stage procedure similar to that described in Example 4.

出典と根拠

ORDレコード: ord-5ce9533c29f84242b8341dbcdb65a59f
出典データセット: uspto-grants-1992_07
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05132469

反応ノート

読み込み中…