HCID 178447116、化合物 → HCID 178455615、化合物
反応式
C(S(C[C@@H](CC1C=CC=CC=1)C(N[C@@H](CC1N=CNC=1)C(N[C@@H](CC1CCCCC1)[C@@H](O)C(O)C(C)(C)C)=O)=O)(=O)=O)(C)(C)C.C(S(C[C@@H](CC1C=CC=CC=1)C(N[C@@H](CC1N=CNC=1)C(N[C@@H](CC1CCCCC1)[C@@H](O)[C@@H](O)C(C)C)=O)=O)(=O)=O)(C)(C)C.[C:90]([S:94]([CH2:97][C@@H:98]([CH2:130][C:131]1[CH:136]=[CH:135][CH:134]=[CH:133][CH:132]=1)[C:99]([NH:101][C@@H:102]([CH2:124][C:125]1[N:126]=[CH:127][NH:128][CH:129]=1)[C:103]([NH:105][C@@H:106]([CH2:117][CH:118]1[CH2:123][CH2:122][CH2:121][CH2:120][CH2:119]1)[C@@H:107]([OH:116])[C@H:108]([CH:110]1[CH2:115][CH2:114][CH2:113][CH2:112][CH2:111]1)[OH:109])=[O:104])=[O:100])(=[O:96])=[O:95])([CH3:93])([CH3:92])[CH3:91]>>[C:90]([S:94]([CH2:97][C@@H:98]([CH2:130][C:131]1[CH:132]=[CH:133][CH:134]=[CH:135][CH:136]=1)[C:99]([NH:101][C@@H:102]([CH2:124][C:125]1[N:126]=[CH:127][NH:128][CH:129]=1)[C:103]([NH:105][C@@H:106]([CH2:117][CH:118]1[CH2:123][CH2:122][CH2:121][CH2:120][CH2:119]1)[C@@H:107]([OH:116])[C@H:108]([OH:109])[C:110]1[CH:111]=[CH:112][CH:113]=[CH:114][CH:115]=1)=[O:104])=[O:100])(=[O:96])=[O:95])([CH3:93])([CH3:91])[CH3:92]参加物
4
実験手順
(S)-α-[(S)-α-[(t-butylsulphonyl)methyl]hydrocinnamamido]-N-[(1S,2R,3RS)-1-(cyclohexylmethyl)-2,3-dihydroxy-4,4-dimethylpentyl]imidazole-4-propionamide; (S)-α-[(S)-α-[(t-butylsulphonyl)methyl]hydrocinnamamido]-N-[(1S,2R,3S)-1-(cyclohexylmethyl)-2,3-dihydroxy-4-methylpentyl]imidazole-4-propionamide; (S)-α-[(S)-α-[(t-butylsulphonyl)methyl]hydrocinnamamido]-N-[(1S,2R,3S)-3-cyclohexyl-1-(cyclohexylmethyl)-2,3-dihydroxypropyl]imidazole-4-propionamide.