5-Phenyl-1-pentanol → Cyclohexanepentanol

HRID 654896ノート

反応式

HRID 654896 の反応式
[C:1]1([CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][OH:12])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[H][H]>C(O)(=O)C.C(OCC)C.[Pt]=O>[CH:1]1([CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][OH:12])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

参加物

6

反応物 2

HCID 615235-Phenyl-1-pentanolHCID 178418361HCID 178418361、化合物

生成物 1

HCID 269450Cyclohexanepentanol

試薬・触媒・溶媒 3

HCID 82844Platinum oxide (PtO)触媒HCID 176Acetic Acid溶媒HCID 3283Diethyl Ether溶媒

実験手順

To a solution of 5-phenylpentanol (2.21 g., 13.5 mmol) in ten ml glacial acetic acid was added amorphous platinum oxide (0.40 g., 1.76 mmol, oxygen activated). This mixture was subjected to three atm. of hydrogen with agitation (Parr hydrogenator) at room temperature for four hours. The reaction mixture was diluted with ethyl ether, filtered through celite, washed repeatedly with saturated sodium bicarbonate, followed by water and saturated sodium chloride solution. The organic portion was filtered, dried over magnesium sulfate, filtered and concentrated to give the desired alcohol.

後処理

  1. filtrationfiltered through celite
  2. washwashed repeatedly with saturated sodium bicarbonate
  3. filtrationThe organic portion was filtered
  4. dry with materialdried over magnesium sulfate
  5. filtrationfiltered
  6. concentrationconcentrated

出典と根拠

ORDレコード
ord-2ecf8f125a674a57bc18840d689fdf3f
出典データセット
uspto-grants-1992_07
特許番号
US05134128

反応ノート

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