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Oxygen → 4-(1-methoxytridecyl)-5-hydroxy-2(5H)-furanone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Oxygen | HCID 977 | — |
| 反応物 | Tetrahydrofuran | HCID 8028 | — |
| 反応物 | Rose Bengal Lactone | HCID 69439 | — |
| 反応物 | 4-(1-Methoxytridecyl)-2-trimethylsilylfuran | HCID 15037058 | — |
| 生成物 | 4-(1-methoxytridecyl)-5-hydroxy-2(5H)-furanone | HCID 15037059 | — |
反応手順
A mixture of 4-(1-methoxytridecyl)-2-trimethylsilylfuran (280 mg, 0.8 mmol) and Rose Bengal (5 mg) in tetrahydrofuran (7 ml) was exposed to singlet oxygen for 5 hr at -78°. The residue, after solvent removal, was flash chromatographed on silica using 60% ethyl ether/petroleum ether. Fractions with Rf of about 0.21 on evaporation afforded the 4-(1-methoxytridecyl)-5-hydroxy-2(5H)-furanone as a colorless prism: mp 53°-4°.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05134128 |
| 出典データセット | uspto-grants-1992_07 |
| ORD ID | ord-644f675e0b2348ab9e3d6f535dd0e83a |
| 出典メモ | uspto-grants-1992_07 |