Methylparaben → Methyl 4-(2-quinolinylmethoxy)benzoate

反応式

[OH:1][C:2]1[CH:11]=[CH:10][C:5]([C:6]([O:8][CH3:9])=[O:7])=[CH:4][CH:3]=1.Cl[CH2:13][C:14]1[CH:23]=[CH:22][C:21]2[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=2)[N:15]=1>>[N:15]1[C:16]2[C:21](=[CH:20][CH:19]=[CH:18][CH:17]=2)[CH:22]=[CH:23][C:14]=1[CH2:13][O:1][C:2]1[CH:3]=[CH:4][C:5]([C:6]([O:8][CH3:9])=[O:7])=[CH:10][CH:11]=1

参加物

反応物 2

HCID 7456Methylparaben

HCID 203942-(Chloromethyl)quinoline

生成物 1

HCID 19934817Methyl 4-(2-quinolinylmethoxy)benzoate収率 88%

実験手順

The title compound was prepared from methyl 4-hydroxybenzoate and 2-chloromethylquinoline using methods as described in the literature for similar compounds (Musser et al., 1990) in 88% yield.

出典と根拠

ORDレコード: ord-fbe2965e1598423e96844cfe7bfb69d8
出典データセット: uspto-grants-2011_12
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08071620B2

反応ノート

読み込み中…