Hydrochloric Acid → HCID 59332581、化合物
反応式
Cl.CC(OC([N:9]1[C:17]2[C:12](=[C:13]([F:21])[CH:14]=[CH:15][C:16]=2[C:18]([OH:20])=[O:19])[CH2:11][CH2:10]1)=O)(C)C>C(Cl)Cl>[F:21][C:13]1[CH:14]=[CH:15][C:16]([C:18]([OH:20])=[O:19])=[C:17]2[C:12]=1[CH2:11][CH2:10][NH:9]2参加物
4
実験手順
A solution of 1 M HCl (1 mL, 1 mmol) was added to a solution of 1-{[(1,1-Dimethylethyl)oxy]carbonyl}-4-fluoro-2,3-dihydro-1H-indole-7-carboxylic acid (50 mg, x mmol) in DCM at room temperature. The reaction was stirred for 2 h, and additional 1 M HCl (1 mL, 1 mmol) was added. The reaction was stirred overnight, and the mixture was evaporated and dried under high vacuum, giving the title compound.
後処理
- stirringThe reaction was stirred overnight
- customthe mixture was evaporated
- customdried under high vacuum
出典と根拠
- ORDレコード
- ord-5eb640061acb4605bd4034808c2239d1
- 出典データセット
- uspto-grants-2011_12
- 特許番号
- US08071584B2
反応ノート
読み込み中…