関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Phosphoric Acid | HCID 1004 | — |
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | 2,2-Dimethyl-4-((phenylmethoxy)methyl)-1,3-dioxolane | HCID 85795 | — |
| 反応物 | 11097-59-9 | HCID 24838866 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 3-(Benzyloxy)-1,2-propanediol | HCID 98072 | — |
反応手順
Into a 1 L beaker were weighed 222 g (1.0 mol) of 4-(benzyloxymethyl)-2,2-dimethyl-1,3-dioxolane prepared in 1-2, 250 ml of ethanol, and 400 ml of distilled water, and the whole was adjusted to pH 2 with phosphoric acid. With introducing nitrogen thereinto, the solution was heated to 70° C. After 1.5 hours of the reaction, the solution was adjusted to pH 7.0 with sodium hydroxide. The resulting salt was subjected to adsorption treatment with an adsorbent “KYOWAAD 1000” (manufactured by Kyowa Hakko Kogyo Co., Ltd.) and then subjected to solvent removal to obtain 3-benzyloxy-1,2-propanediol.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08071712B2 |
|---|
| 出典データセット | uspto-grants-2011_12 |
|---|
| ORD ID | ord-df30cbdd00a54e0bb1676e48eb262a3f |
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| 出典メモ | uspto-grants-2011_12 |
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