8-methylsulfonyl-12(R)-hydroxy-10-heptadecynoic acid → 8-methylsulfonyl-12(R)-hydroxyheptadecanoic acid

HRID 65648ノート

反応式

HRID 65648 の反応式
[CH3:1][S:2]([CH:5]([CH2:15][C:16]#[C:17][C@@H:18]([OH:24])[CH2:19][CH2:20][CH2:21][CH2:22][CH3:23])[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][C:12]([OH:14])=[O:13])(=[O:4])=[O:3].CS(C(CC#C[C@H](O)CCCCC)CCCCCCC(O)=O)(=O)=O>>[CH3:1][S:2]([CH:5]([CH2:15][CH2:16][CH2:17][C@H:18]([OH:24])[CH2:19][CH2:20][CH2:21][CH2:22][CH3:23])[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][C:12]([OH:14])=[O:13])(=[O:3])=[O:4]

参加物

3

反応物 2

HCID 227969748-methylsulfonyl-12(R)-hydroxy-10-heptadecynoic acidHCID 227969758-methylsulfonyl-12(S)-hydroxy-10-heptadecynoic acid

生成物 1

HCID 227969778-methylsulfonyl-12(R)-hydroxyheptadecanoic acid

実験手順

The synthesis of this compound is carried out by the procedure described in Example 15 except that the 8-methylsulfonyl-12(S)-hydroxy-10-heptadecynoic acid is replaced by an equivalent quantity of 8-methylsulfonyl-12(R)-hydroxy-10-heptadecynoic acid.

後処理

  1. customThe synthesis of this compound

出典と根拠

ORDレコード
ord-01fd0c81c8b443489d2e790f658881ed
出典データセット
uspto-grants-1978_12
特許番号
US04128564

反応ノート

読み込み中…