1,8-Diazabicyclo(5.4.0)undec-7-ene → 1-(2-Cyclopropylethenyl)-2-nitrobenzene
反応式
Cl[CH:2]([CH:13]1[CH2:15][CH2:14]1)[CH2:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[N+:10]([O-:12])=[O:11].N12CCCN=C1CCCCC2>O1CCOCC1>[CH:13]1([CH:2]=[CH:3][C:4]2[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=2[N+:10]([O-:12])=[O:11])[CH2:15][CH2:14]1参加物
4
実験手順
To 1 g (4.25 mmol, purity 96%) of 1-(2-chloro-2-cyclopropylethyl)-2-nitrobenzene in 20 ml of dioxane is added 0.65 g (4.25 mmol) of 1,8-diazabicyclo(5.4.0)undec-7-ene, and the mixture is stirred at room temperature for 12 h. Subsequently, the solvent is concentrated under reduced pressure and the residue is admixed with ethyl acetate and water. After the organic phases have been removed and the solvent has been concentrated by evaporation, 0.7 g (79% of theory) of 1-[2-cyclopropylvinyl]-2-nitrobenzene is obtained.
後処理
- concentrationSubsequently, the solvent is concentrated under reduced pressure
- customAfter the organic phases have been removed
- concentrationthe solvent has been concentrated by evaporation
出典と根拠
- ORDレコード
- ord-5b668dae0c99493ebe7849fde34182b6
- 出典データセット
- uspto-grants-2011_12
- 特許番号
- US08071824B2
反応ノート
読み込み中…