Allyl iodide → HCID 68993985、化合物
反応式
[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[C:8]([C:11]#[N:12])[CH:9]=2)[CH:4]=[CH:3][CH:2]=1.[CH2:13]([I:16])[CH:14]=[CH2:15]>C1(C)C=CC=CC=1>[I-:16].[C:11]([C:8]1[CH:9]=[C:10]2[C:5]([CH:4]=[CH:3][CH:2]=[N+:1]2[CH2:15][CH:14]=[CH2:13])=[CH:6][CH:7]=1)#[N:12]参加物
4
実験手順
7-Quinolinecarbonitrile (1.01 g, 6.6 mmol) and allyl iodide (1.2 mL, 13.2 mmol) in toluene (10 ml) was heated at 90° C. then at 120° C. for 2 h. More allyl iodide was then added (1.2 ml, 13.2 mmol). After other 2 h more allyl iodide was added (1.2 ml, 13.2 mmol). After 2 h more the reaction was cooled to rt. The solid was filtered off, washed with toluene and dried in vacuo at 45° C. overnight to afford the desired compound (1.75 g, 82%).
後処理
- filtrationThe solid was filtered off
- washwashed with toluene
- customdried in vacuo at 45° C. overnight
出典と根拠
- ORDレコード
- ord-31651089a8744f9b90a1ab9511b6e2c9
- 出典データセット
- uspto-grants-2011_12
- 特許番号
- US08071592B2
反応ノート
読み込み中…