化工社化工社 化学情報印刷レポート · 研究参考用
Paclitaxel → Baccatin Iii
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Paclitaxel | HCID 36314 | — |
| 反応物 | 7-Epi-Taxol | HCID 184492 | — |
| 生成物 | Baccatin Iii | HCID 65366 | — |
反応手順
Degradation products were formed in the same proportions as in the experiments conducted under room temperature but in significantly lower quantities. Again, 7-epi-taxol was the main degradation product of paclitaxel (10% at pH 8.0). Baccatin III and 10-deacethyltaxol were formed for about 5 to 6% at pH 8.0. Found unknown substances were the same.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08075913B2 |
| 出典データセット | uspto-grants-2011_12 |
| ORD ID | ord-19871fd22d5c45abb55394df7344fe92 |
| 出典メモ | uspto-grants-2011_12 |