2-Hydrazinopyridine → 3-TERT-BUTYL-1-(PYRIDIN-2-YL)-1H-PYRAZOL-5-AMINE

反応式

[CH3:1][C:2]([CH3:9])([CH3:8])[C:3](=O)[CH2:4][C:5]#[N:6].[NH:10]([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][N:13]=1)[NH2:11]>>[C:2]([C:3]1[CH:4]=[C:5]([NH2:6])[N:10]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][N:13]=2)[N:11]=1)([CH3:9])([CH3:8])[CH3:1]

参加物

反応物 2

HCID 786452-Hydrazinopyridine

HCID 108871Pentanenitrile, 4,4-dimethyl-3-oxo-

生成物 1

HCID 433813303-TERT-BUTYL-1-(PYRIDIN-2-YL)-1H-PYRAZOL-5-AMINE収率 99%

実験手順

The title compound was prepared from 4,4-dimethyl-3-oxopentane nitrile and 2-hydrazinopyridine, using the same method as that described for preparation 7, as a solid in 99% yield.

後処理

customthat described for preparation 7, as a solid in 99% yield

出典と根拠

ORDレコード: ord-602efdbb90324ac78b178b07e68ae827
出典データセット: uspto-grants-2011_12
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08076356B2

反応ノート

読み込み中…