1,1-Dimethylhydrazine → alpha-Dimethylhydrazinocarbonylamino-2-thiopheneacetic acid
反応式
[N:1]([CH:4]([C:10]1[S:11][CH:12]=[CH:13][CH:14]=1)[C:5]([O:7]CC)=[O:6])=[C:2]=[O:3].[CH3:15][N:16]([CH3:18])[NH2:17].C(Cl)Cl>C(O)(=O)C>[CH3:15][N:16]([CH3:18])[NH:17][C:2]([NH:1][CH:4]([C:10]1[S:11][CH:12]=[CH:13][CH:14]=1)[C:5]([OH:7])=[O:6])=[O:3]参加物
5
実験手順
A solution of 4.2 g. (0.02 mole) of DL-α-isocyanato-2-thiopheneacetic acid, ethyl ester and 1.2 g. (0.02 mole) of N,N-dimethylhydrazine in 80 ml. of methylene chloride is stirred overnight. The solution is concentrated and to the syrupy residue are added 10 ml. of 2N sodium hydroxide solution. After stirring for 30 minutes, a clear yellow solution results. By the addition of acetic acid, 3.9 g. of α-dimethylhydrazinocarbonylamino-2-thiopheneacetic acid are obtained, m.p. 208°-210°.
後処理
- concentrationThe solution is concentrated and to the syrupy residue
- additionare added 10 ml
- customa clear yellow solution results
出典と根拠
- ORDレコード
- ord-208d1fa98d07437e8ee5455d106b3405
- 出典データセット
- uspto-grants-1978_12
- 特許番号
- US04128724
反応ノート
読み込み中…