Glutaric Acid → HCID 178484388、化合物
反応式
[CH3:1][N:2]([C:4]([NH:6][C:7]([NH2:9])=[NH:8])=[NH:5])[CH3:3].[C:10]([OH:18])(=[O:17])[CH2:11][CH2:12][CH2:13][C:14]([OH:16])=[O:15].C(OCC)(=O)C>CO>[CH3:1][N:2]([C:4]([NH:6][C:7]([NH2:9])=[NH:8])=[NH:5])[CH3:3].[C:10]([O-:18])(=[O:17])[CH2:11][CH2:12][CH2:13][C:14]([O-:16])=[O:15]参加物
5
実験手順
10.0 g of the metformin free-base and 3.98 g of glutaric acid were stirred in 100 ml of methyl alcohol at a temperature of 40° C., and then ethyl acetate was added thereto. The produced crystal was filtered and dried in hot air, thus obtaining 5.15 g (yield: 43.8%) of metformin glutarate.
後処理
- filtrationThe produced crystal was filtered
- customdried in hot air
出典と根拠
- ORDレコード
- ord-d99303c04d69446cad2b4281e2f52d51
- 出典データセット
- uspto-grants-2011_12
- 特許番号
- US08076377B2
反応ノート
読み込み中…