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HRID 6587作成日:2026年10月24日

(R)-(+)-1,1,1-trifluoro-2-octyl 4-benzyloxybenzoate → 4-hydroxybenzoic acid (R)-1-trifluoromethyl-heptyl ester

https://huagongshe.com/ja/reaction/6587

反応式

関与物質

役割名称HCID仕込み量
反応物(R)-(+)-1,1,1-trifluoro-2-octyl 4-benzyloxybenzoateHCID 22850730—
溶媒Ethyl AcetateHCID 8857—
生成物4-hydroxybenzoic acid (R)-1-trifluoromethyl-heptyl esterHCID 1454921799%

反応手順

2.2 g of [R]-1-trifluoromethylheptyl 4-benzyloxybenzoate, (13) 100 mg of PdOH/C in 50 ml of ethyl acetate was stirred at RT over night under H2 atmosphere. Then the catalyst was filtered out and filtrate was evaporated to dryness to give the pure compound in yield of 99%.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US07083832B2
出典データセットuspto-grants-2006_08
ORD IDord-3687b0a5c976428fb52ff00b4203cdb7
出典メモuspto-grants-2006_08