化工社化工社 化学情報印刷レポート · 研究参考用
(R)-(+)-1,1,1-trifluoro-2-octyl 4-benzyloxybenzoate → 4-hydroxybenzoic acid (R)-1-trifluoromethyl-heptyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | (R)-(+)-1,1,1-trifluoro-2-octyl 4-benzyloxybenzoate | HCID 22850730 | — |
| 溶媒 | Ethyl Acetate | HCID 8857 | — |
| 生成物 | 4-hydroxybenzoic acid (R)-1-trifluoromethyl-heptyl ester | HCID 14549217 | 99% |
反応手順
2.2 g of [R]-1-trifluoromethylheptyl 4-benzyloxybenzoate, (13) 100 mg of PdOH/C in 50 ml of ethyl acetate was stirred at RT over night under H2 atmosphere. Then the catalyst was filtered out and filtrate was evaporated to dryness to give the pure compound in yield of 99%.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07083832B2 |
| 出典データセット | uspto-grants-2006_08 |
| ORD ID | ord-3687b0a5c976428fb52ff00b4203cdb7 |
| 出典メモ | uspto-grants-2006_08 |