3-(t-Butyldimethylsilyloxy)benzaldehyde → HCID 59524397、化合物

反応式

[Si:1]([O:8][C:9]1[CH:10]=[C:11]([CH:14]=[CH:15][CH:16]=1)[CH:12]=O)([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2].Cl.[NH2:18][C:19]([CH3:26])([CH2:24][OH:25])[C:20]([O:22][CH3:23])=[O:21]>>[Si:1]([O:8][C:9]1[CH:10]=[C:11]([CH:14]=[CH:15][CH:16]=1)[CH2:12][NH:18][C:19]([CH3:26])([CH2:24][OH:25])[C:20]([O:22][CH3:23])=[O:21])([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2]

参加物

反応物 2

HCID 112071113-(t-Butyldimethylsilyloxy)benzaldehyde

HCID 13221872Methyl 2-amino-3-hydroxy-2-methylpropanoate hydrochloride

生成物 1

HCID 59524397HCID 59524397、化合物収率 97%

実験手順

Prepare as in Example 12-9c from 3-(tert-butyldimethylsilyloxy)benzaldehyde (Example 12-1c) and methyl 2-amino-3-hydroxy-2-methylpropanoate hydrochloride. Yield 97%, yellowish oil. MS 354 (MH+).

出典と根拠

ORDレコード: ord-eb79089fe8aa45eeb17224320884548a
出典データセット: uspto-grants-2011_12
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08076491B2

反応ノート

読み込み中…