化工社化工社 化学情報印刷レポート · 研究参考用
4-Amino-1-butanol → 1-(4-Chloro-3-trifluoromethylphenyl)-3-{4-[2-(3-hydroxy-butylamino)-pyrimidin-4-yloxy]-phenyl}-urea
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Amino-1-butanol | HCID 25868 | — |
| 反応物 | 2-Butanol, 4-amino- | HCID 170254 | — |
| 反応物 | 1-(4-Chloro-3-trifluoromethyl-phenyl)-3-[4-(2-methanesulfonyl-pyrimidin-4-yloxy)-phenyl]-urea | HCID 67523920 | — |
| 生成物 | 1-(4-Chloro-3-trifluoromethylphenyl)-3-{4-[2-(3-hydroxy-butylamino)-pyrimidin-4-yloxy]-phenyl}-urea | HCID 24997655 | — |
反応手順
The compound was prepared from 1-(4-Chloro-3-trifluoromethyl-phenyl)-3-[4-(2-methanesulfonyl-pyrimidin-4-yloxy)-phenyl]-urea and 4-amino-butan-2-ol as described in example 10 for 4-amino-butan-1-ol instead.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08080552B2 |
| 出典データセット | uspto-grants-2011_12 |
| ORD ID | ord-06a37e85bbef4f9e8561b9c2e1c85ca2 |
| 出典メモ | uspto-grants-2011_12 |