Acetic Anhydride → Isoxazolo(3,4-d)pyrimidine-4,6(5H,7H)-dione, 3,5,7-trimethyl-
反応式
[CH3:1][N:2]1[C:9]([NH:10][OH:11])=[CH:8][C:6](=[O:7])[N:5]([CH3:12])[C:3]1=[O:4].[C:13](OC(=O)C)(=O)[CH3:14]>>[CH3:13][C:14]1[O:11][N:10]=[C:9]2[C:8]=1[C:6](=[O:7])[N:5]([CH3:12])[C:3](=[O:4])[N:2]2[CH3:1]参加物
3
実験手順
One gram of 1,3-dimethyl-6-hydroxyaminouracil is boiled with 10 ml of acetic anhydride at 140° C. for 1 hour and, when hot, the insolubles are filtered off. The filtrate is concentrated to dryness to recover 0.7 g of the captioned compound as colorless needles. As recrystallized from ethanol, the compound melts at 200°-202° C.
後処理
- filtrationwhen hot, the insolubles are filtered off
- concentrationThe filtrate is concentrated to dryness
- customto recover 0.7 g of the captioned compound as colorless needles
- customAs recrystallized from ethanol
出典と根拠
- ORDレコード
- ord-325744882a9341599ac683156f0a193a
- 出典データセット
- uspto-grants-1978_12
- 特許番号
- US04129654
反応ノート
読み込み中…