化工社化工社 化学情報印刷レポート · 研究参考用
Methyl 2-iodo-4-(trifluoromethyl)benzoate → 2-Cyclobutyl-4-trifluoromethyl-benzoic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methyl 2-iodo-4-(trifluoromethyl)benzoate | HCID 59438424 | — |
| 反応物 | 2-Cyclopropyl-4-(trifluoromethyl)benzoic acid | HCID 59438485 | — |
| 反応物 | HCID 178419766 | HCID 178419766 | — |
| 生成物 | 2-Cyclobutyl-4-trifluoromethyl-benzoic acid | HCID 59438432 | — |
反応手順
The title compound, white solid, MS: m/e=243.0 [(M−H)−], was prepared in accordance with the general method of intermediate K from 2-iodo-4-trifluoromethyl-benzoic acid methyl Ester and cyclobutylzincbromide followed by saponification with sodium hydroxide.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08080541B2 |
| 出典データセット | uspto-grants-2011_12 |
| ORD ID | ord-459820a8946d40eab6c887b0d71dd365 |
| 出典メモ | uspto-grants-2011_12 |