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HRID 659266作成日：2026年10月26日

2-Methoxy-4,6-bis(trifluoromethyl)benzoic acid → cis-2-Methoxy-N-(2-pyrrolidin-1-yl-cyclopentyl)-4,6-bis-trifluoromethyl-benzamide

https://huagongshe.com/reaction/659266

反応式

関与物質

役割名称HCID仕込み量
反応物2-Methoxy-4,6-bis(trifluoromethyl)benzoic acidHCID 2741287—
反応物cis-2-Pyrrolidin-1-yl-cyclopentylamineHCID 30820884—
生成物cis-2-Methoxy-N-(2-pyrrolidin-1-yl-cyclopentyl)-4,6-bis-trifluoromethyl-benzamideHCID 86651462—

反応手順

The title compound, white solid, MS: m/e=425.2 [(M+H)+], was prepared in accordance with the general method of example 5 from cis-2-pyrrolidin-1-yl-cyclopentylamine (intermediate Q) and 2-methoxy-4,6-bis(trifluoromethyl)benzoic acid.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US08080541B2
出典データセットuspto-grants-2011_12
ORD IDord-00c86bf1f0434c1686e045d62fca7415
出典メモuspto-grants-2011_12