化工社化工社 化学情報印刷レポート · 研究参考用
2-Methyl-4-(trifluoromethyl)benzoic acid → cis-2-Methyl-N-(2-pyrrolidin-1-yl-cyclopentyl)-4-trifluoromethyl-benzamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Methyl-4-(trifluoromethyl)benzoic acid | HCID 22211658 | — |
| 反応物 | cis-2-Pyrrolidin-1-yl-cyclopentylamine | HCID 30820884 | — |
| 生成物 | cis-2-Methyl-N-(2-pyrrolidin-1-yl-cyclopentyl)-4-trifluoromethyl-benzamide | HCID 66681436 | — |
反応手順
The title compound, yellow gum, MS: m/e=341.3 [(M+H)+], was prepared in accordance with the general method of example 5 from cis-2-pyrrolidin-1-yl-cyclopentylamine (intermediate Q) and 2-methyl-4-trifluoromethyl-benzoic acid (CAS 23984-82-9).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08080541B2 |
| 出典データセット | uspto-grants-2011_12 |
| ORD ID | ord-af7cf134df8a43c4bb13298514395785 |
| 出典メモ | uspto-grants-2011_12 |