戻る
化工社化工社 化学情報印刷レポート · 研究参考用
HRID 659303作成日：2026年10月27日

2-Cyclopropyl-4,6-bis-trifluoromethyl-benzoic acid → 2-Cyclopropyl-N-((cis)-2-pyrrolidin-1-yl-cyclohexyl)-4,6-bis-trifluoromethyl-benzamide

https://huagongshe.com/reaction/659303

反応式

関与物質

役割名称HCID仕込み量
反応物2-Cyclopropyl-4,6-bis-trifluoromethyl-benzoic acidHCID 58167765—
反応物cis-2-Pyrrolidin-1-yl-cyclohexylamine dihydrochlorideHCID 66680564—
生成物2-Cyclopropyl-N-((cis)-2-pyrrolidin-1-yl-cyclohexyl)-4,6-bis-trifluoromethyl-benzamideHCID 51001328—

反応手順

The title compound, white solid, MS: m/e=449.3 [(M+H)+], was prepared in accordance with the general method of example 5 from cis-2-pyrrolidin-1-yl-cyclohexylamine dihydrochloride (intermediate F) and 2-cyclopropyl-4,6-bis-trifluoromethyl-benzoic acid (intermediate AN).

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US08080541B2
出典データセットuspto-grants-2011_12
ORD IDord-294afdd55473481ea83bac75f9291707
出典メモuspto-grants-2011_12