Ammonia → 5-Chloro-2-methyl-6-sulfamoyl-1-indanone

反応式

[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][C:10]=1[S:11](Cl)(=[O:13])=[O:12])[C:7](=[O:15])[CH:6]([CH3:16])[CH2:5]2.[NH3:17]>>[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][C:10]=1[S:11](=[O:13])(=[O:12])[NH2:17])[C:7](=[O:15])[CH:6]([CH3:16])[CH2:5]2

参加物

反応物 2

HCID 222Ammonia

HCID 227563815-Chloro-6-chlorosulfonyl-2-methyl-1-indanone

生成物 1

HCID 227564065-Chloro-2-methyl-6-sulfamoyl-1-indanone

実験手順

According to Example 1 (d), the reaction of 5-chloro-6-chlorosulfonyl-2-methyl-1-indanone with liquid ammonia yields the raw product having a melting point of from 180° to 184° C. After recrystallization from ethanol, the compound melts at 190° to 192° C.

出典と根拠

ORDレコード: ord-c9faffb31803428eb70b596ae6b5c989
出典データセット: uspto-grants-1978_12
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04129656

反応ノート

読み込み中…