化工社化工社 化学情報印刷レポート · 研究参考用
2-Methyl-2-thiopseudourea sulfate → Guanidine Sulfate (1:1)
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Methyl-2-thiopseudourea sulfate | HCID 75270 | — |
| 反応物 | HCID 178433288 | HCID 178433288 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | Guanidine Sulfate (1:1) | HCID 499987 | 103.1% |
反応手順
A solution of 4-methyl-5-((2-aminoethyl)thiomethyl)imidazole (19.0 g.) and S-methylisothiourea sulphate (15.1 g.) in water (100 ml.) was heated under reflux for 3 hours. Concentration, acidification with sulphuric acid and dilution with ethanol afforded 2-[(4-methyl-5-imidazolyl)methylthio)ethyl]guanidine sulphate (13.0 g.) m.p. 230°-235° (from aqueous methanol).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04129657 |
| 出典データセット | uspto-grants-1978_12 |
| ORD ID | ord-d142530121634bff9dac22d3af7bde46 |
| 出典メモ | uspto-grants-1978_12 |