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HRID 659591作成日：2026年10月26日

1-(Cyclohexylmethyl)piperazine → (4-{1-[5-Chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl}phenyl)-[4-(cyclohexylmethyl)piperazin-1-yl]methanone

https://huagongshe.com/reaction/659591

反応式

関与物質

役割名称HCID仕込み量
反応物1-(Cyclohexylmethyl)piperazineHCID 2735885—
反応物4-{1-[5-Chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl}benzoic acidHCID 46906718—
生成物(4-{1-[5-Chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl}phenyl)-[4-(cyclohexylmethyl)piperazin-1-yl]methanoneHCID 58327924—

反応手順

4-{1-[5-chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl}benzoic acid was reacted with 1-(cyclohexylmethyl)piperazine as in General Procedure 10 to give the title compound. LCMS: m/z=611.96 (M+H+); retention time=0.64 minutes.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US08080561B2
出典データセットuspto-grants-2011_12
ORD IDord-3132a3a6684c4bd1b99eec40c3877cc6
出典メモuspto-grants-2011_12