Propyl mercaptan → HCID 178460779、化合物

反応式

[CH2:1]([S:6][C:7]1[C:8]([CH:12]2[CH:17]3[CH2:18][CH2:19][N:14]([CH2:15][CH2:16]3)[CH2:13]2)=[N:9][NH:10][CH:11]=1)[CH2:2][CH2:3]CC.C(S)CC>>[CH2:1]([S:6][C:7]1[C:8]([CH:12]2[CH:17]3[CH2:18][CH2:19][N:14]([CH2:15][CH2:16]3)[CH2:13]2)=[N:9][NH:10][CH:11]=1)[CH2:2][CH3:3]

参加物

反応物 2

HCID 7848Propyl mercaptan

HCID 178447695HCID 178447695、化合物

生成物 1

HCID 178460779HCID 178460779、化合物収率 25%

実験手順

Compound 49E was prepared following the procedure as described for the synthesis of compound 49B (see Scheme 10) using propane-1-thiol as reagent. Subsequent purification by flash chromatography (EtOH to EtOH/triethylamine 99/1) afforded compound 49E.

後処理

customSubsequent purification by flash chromatography (EtOH to EtOH/triethylamine 99/1)

出典と根拠

ORDレコード: ord-909923f880864786aec964dfb6b4635d
出典データセット: uspto-grants-2011_12
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08084473B2

反応ノート

読み込み中…