化工社化工社 化学情報印刷レポート · 研究参考用
2-(4-Nitrophenyl)propionic acid → 4-Aminohydratropic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-(4-Nitrophenyl)propionic acid | HCID 89244 | — |
| 触媒 | Palladium | HCID 23938 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | 4-Aminohydratropic acid | HCID 43026 | — |
反応手順
A mixture of 1 (6.7 g, 1 mmol) in THF (100 ml) and EtOH (100 ml) is slowly added 10% Pd/C (680 mg) at room temperature. The reaction mixture is hydrogenated for 24 h with H2 balloon at room temperature. The mixture is filtered through celite pad and washed with EtOH. The filtrate is concentrated in vacuo.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08084484B2 |
| 出典データセット | uspto-grants-2011_12 |
| ORD ID | ord-fdc8fedb933d421686298bc443ce1c81 |
| 出典メモ | uspto-grants-2011_12 |