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Diethyl Ether → [4-(Benzyloxy)benzyl](triphenyl)phosphonium chloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Diethyl Ether | HCID 3283 | — |
| 反応物 | Triphenylphosphine | HCID 11776 | — |
| 反応物 | 4-Benzyloxybenzyl chloride | HCID 70042 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | [4-(Benzyloxy)benzyl](triphenyl)phosphonium chloride | HCID 383834 | — |
反応手順
4-Benzyloxybenzyl chloride (1 g, 0.0043 mol) and triphenyl phosphine (1.127 g, 1 equivalent) in anhydrous toluene (20 mL) were refluxed under nitrogen for ˜8–10 hours. A white precipitate appeared in the reaction mixture. The reaction mixture was then cooled to room temperature and ether (100 mL) was added. The precipitated phosphonium salt was collected by filtration, rinsed with ether and air dried. Yield=0.55 g (25%). MALDI-TOF MS 459.51 obs. (459.54 calc.).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07083986B2 |
| 出典データセット | uspto-grants-2006_08 |
| ORD ID | ord-10387fc676524c57a88f49116ff26a5c |
| 出典メモ | uspto-grants-2006_08 |