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Hydrochloric Acid → 1,4-Bis(4-chlorophenyl)-2-butene-1,4-dione
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Chlorobenzene | HCID 7964 | — |
| 反応物 | Fumaryl chloride | HCID 5325504 | — |
| 反応物 | Aluminum(III) Chloride | HCID 6451240 | — |
| 溶媒 | Carbon Disulfide | HCID 6348 | — |
| 生成物 | 1,4-Bis(4-chlorophenyl)-2-butene-1,4-dione | HCID 232001 | — |
反応手順
Chlorobenzene (0.4 mol) and aluminium chloride (0.5 mol) in carbon disulphide (30 ml) were stirred at 50°-60°. Fumaryl chloride (0.2 mol) was added dropwise at a brisk rate over 30 minutes and refluxing was continued for a further 15 minutes. The residue was poured into crushed ice (1 kg) and concentrated hydrochloric acid (15.0 ml). The semi-solid was filtered off, washed with ether and ethanol, and recrystallised from ethyl acetate/ethanol to give pale yellow needles of di-(p-chlorobenzoyl) ethylene m.p. 175°-176°. Analysis:
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04130409 |
| 出典データセット | uspto-grants-1978_12 |
| ORD ID | ord-7268eb315e164f72ba51cc9181c1bd1a |
| 出典メモ | uspto-grants-1978_12 |