化工社化工社 化学情報印刷レポート · 研究参考用
Sodium Hydroxide → Ampicillin Sodium
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | Ampicillin Trihydrate | HCID 23565 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | Ampicillin Sodium | HCID 23663979 | — |
反応手順
A suspension of 2.418 kg (6 mols) of ampicillin trihydrate in 15 liters of water was admixed with 300 ml of 2N sodium hydroxide, and the sodium ampicillin was isolated as a snow-white powder by lyophilization in the same manner and under the exact same conditions as in Example 1. The product was storage-stable and showed an active substance content of 91.5% in the microbiological test and 92.7% in the iodometric test.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04130558 |
| 出典データセット | uspto-grants-1978_12 |
| ORD ID | ord-0fed73dba5484d938aee81dfc0700611 |
| 出典メモ | uspto-grants-1978_12 |