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HRID 66054作成日:2026年10月26日

Sodium Hydroxide → Ampicillin Sodium

https://huagongshe.com/reaction/66054

反応式

関与物質

役割名称HCID仕込み量
反応物Sodium HydroxideHCID 14798—
反応物Ampicillin TrihydrateHCID 23565—
溶媒WaterHCID 962—
生成物Ampicillin SodiumHCID 23663979—

反応手順

A suspension of 2.418 kg (6 mols) of ampicillin trihydrate in 15 liters of water was admixed with 300 ml of 2N sodium hydroxide, and the sodium ampicillin was isolated as a snow-white powder by lyophilization in the same manner and under the exact same conditions as in Example 1. The product was storage-stable and showed an active substance content of 91.5% in the microbiological test and 92.7% in the iodometric test.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US04130558
出典データセットuspto-grants-1978_12
ORD IDord-0fed73dba5484d938aee81dfc0700611
出典メモuspto-grants-1978_12