Water → 2-Methylsulfanylbenzene-1,3-diol

HRID 660625ノート

反応式

HRID 660625 の反応式
C[O:2][C:3]1[CH:8]=[CH:7][CH:6]=[C:5]([O:9]C)[C:4]=1[S:11][CH3:12].B(Br)(Br)Br.O>C(Cl)Cl>[CH3:12][S:11][C:4]1[C:5]([OH:9])=[CH:6][CH:7]=[CH:8][C:3]=1[OH:2]

参加物

5

反応物 3

HCID 962WaterHCID 25134Boron tribromideHCID 6035511,3-Dimethoxy-2-(methylthio)benzene

生成物 1

HCID 688384622-Methylsulfanylbenzene-1,3-diol

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

To a solution of 1,3-dimethoxy-2-methylsulfanylbenzene (2.8 g, 15 mmol) in methylene chloride (40 mL) is added BBr3 (30 mL, 30 mmol, 1M in methylene chloride) and the mixture is stirred at RT for 18 h. Water is added and the organic phase is washed with water and brine then is dried over sodium sulfate. The solvent is removed under reduced pressure to give the title compound as a pink solid.

後処理

  1. washthe organic phase is washed with water and brine
  2. dry with materialthen is dried over sodium sulfate
  3. customThe solvent is removed under reduced pressure

出典と根拠

ORDレコード
ord-3ec0328fb0414ce58ff7ecdc49182672
出典データセット
uspto-grants-2011_12
特許番号
US08084448B2

反応ノート

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