2-[(4-Ethynyl-2-Fluorophenyl)amino]-3,4-Difluoro-N-(2-Hydroxyethoxy)-5-{[(2-Hydroxyethoxy)imino]methyl}benzamide → 2-(4-ethynyl-2-fluoroanilino)-3,4-difluoro-N-(2-hydroxyethoxy)-5-[(E)-[3-(methylamino)-3-oxopropoxy]iminomethyl]benzamide

反応式

[F:1][C:2]1[C:3]([NH:25][C:26]2[CH:31]=[CH:30][C:29](I)=[CH:28][C:27]=2[F:33])=[C:4]([CH:12]=[C:13]([CH:16]=[N:17][O:18][CH2:19][CH2:20][C:21](=[O:24])[NH:22][CH3:23])[C:14]=1[F:15])[C:5]([NH:7][O:8][CH2:9][CH2:10][OH:11])=[O:6].[C:34](C1C=CC(NC2C(F)=C(F)C(C=NOCCO)=CC=2C(NOCCO)=O)=C(F)C=1)#[CH:35].C(C1C=CC(NC2C(F)=C(F)C(/C=N/OCCO)=CC=2C(NOCCO)=O)=C(F)C=1)#C>>[C:34]([C:29]1[CH:30]=[CH:31][C:26]([NH:25][C:3]2[C:2]([F:1])=[C:14]([F:15])[C:13](/[CH:16]=[N:17]/[O:18][CH2:19][CH2:20][C:21](=[O:24])[NH:22][CH3:23])=[CH:12][C:4]=2[C:5]([NH:7][O:8][CH2:9][CH2:10][OH:11])=[O:6])=[C:27]([F:33])[CH:28]=1)#[CH:35]