4-Chlorophenol → N-cyanoethyl p-fluorophenoxy isobutyramide

反応式

ClC1C=CC(O)=CC=1.[F:9][C:10]1[CH:15]=[CH:14][C:13]([OH:16])=[CH:12][CH:11]=1.[C:17]([CH2:19][CH2:20][NH:21][C:22](=[O:27])[C:23](Br)([CH3:25])[CH3:24])#[N:18]>>[C:17]([CH2:19][CH2:20][NH:21][C:22](=[O:27])[C:23]([O:16][C:13]1[CH:14]=[CH:15][C:10]([F:9])=[CH:11][CH:12]=1)([CH3:25])[CH3:24])#[N:18]

参加物

反応物 3

HCID 46844-Chlorophenol

HCID 97324-Fluorophenol

HCID 54029148N-cyanoethyl alpha-bromo-isobutyramide

生成物 1

HCID 85921733N-cyanoethyl p-fluorophenoxy isobutyramide

実験手順

The procedure of Example 1 was repeated except that the p-chlorophenol was replaced by p-fluorophenol, which after the dodium treatment was reacted with N-Cyanoethyl α -bromo-isobutyramide.

出典と根拠

ORDレコード: ord-3e51f99993564123ab56d7492618b4f1
出典データセット: uspto-grants-1978_12
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04131617

反応ノート

読み込み中…