Selenium Dioxide → 2-Methoxyphenylglyoxal hydrate
反応式
C[O:2][CH2:3][C:4]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)=[O:5].[Se](=O)=O.[O:15]1CCOC[CH2:16]1>O.C(OCC)(=O)C>[OH2:2].[CH3:16][O:15][C:7]1[CH:8]=[CH:9][CH:10]=[CH:11][C:6]=1[C:4]([CH:3]=[O:2])=[O:5]参加物
6
実験手順
3 g of 2-methoxyacetophenone are dissolved in 15 ml of dioxane, and a solution of 3.3 g of selenium dioxide in 1.5 ml of water is added thereto. The solution is refluxed for 15 hours. After the reaction, insoluble materials are removed by filtration, and the filtrate is concentrated. The oily residue thus obtained is dissolved in ethyl acetate. The ethyl acetate solution is washed with water and then with an aqueous sodium bicarbonate solution and water. Then, said solution is dried and evaporated to remove solvent. 3.1 g of 2-methoxyphenylglyoxal hydrate are obtained as a crude oil.
後処理
- temperatureThe solution is refluxed for 15 hours
- customAfter the reaction, insoluble materials
- customare removed by filtration
- concentrationthe filtrate is concentrated
- customThe oily residue thus obtained
- washThe ethyl acetate solution is washed with water
- customis dried
- customevaporated
- customto remove solvent
出典と根拠
- ORDレコード
- ord-d7ae0d83b4204e4da29186e8c627e9d9
- 出典データセット
- uspto-grants-1978_12
- 特許番号
- US04131686
反応ノート
読み込み中…