Selenium Dioxide → 2-Methoxyphenylglyoxal hydrate

HRID 66318

反応式

HRID 66318 の反応式
C[O:2][CH2:3][C:4]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)=[O:5].[Se](=O)=O.[O:15]1CCOC[CH2:16]1>O.C(OCC)(=O)C>[OH2:2].[CH3:16][O:15][C:7]1[CH:8]=[CH:9][CH:10]=[CH:11][C:6]=1[C:4]([CH:3]=[O:2])=[O:5]

参加物

6

反応物 3

HCID 24007Selenium DioxideHCID 312751,4-DioxaneHCID 776982-Methoxy-1-phenylethanone

生成物 1

HCID 204341102-Methoxyphenylglyoxal hydrate

試薬・触媒・溶媒 2

HCID 962Water溶媒HCID 8857Ethyl Acetate溶媒

実験手順

3 g of 2-methoxyacetophenone are dissolved in 15 ml of dioxane, and a solution of 3.3 g of selenium dioxide in 1.5 ml of water is added thereto. The solution is refluxed for 15 hours. After the reaction, insoluble materials are removed by filtration, and the filtrate is concentrated. The oily residue thus obtained is dissolved in ethyl acetate. The ethyl acetate solution is washed with water and then with an aqueous sodium bicarbonate solution and water. Then, said solution is dried and evaporated to remove solvent. 3.1 g of 2-methoxyphenylglyoxal hydrate are obtained as a crude oil.

後処理

  1. temperatureThe solution is refluxed for 15 hours
  2. customAfter the reaction, insoluble materials
  3. customare removed by filtration
  4. concentrationthe filtrate is concentrated
  5. customThe oily residue thus obtained
  6. washThe ethyl acetate solution is washed with water
  7. customis dried
  8. customevaporated
  9. customto remove solvent

出典と根拠

ORDレコード
ord-d7ae0d83b4204e4da29186e8c627e9d9
出典データセット
uspto-grants-1978_12
特許番号
US04131686

関連ノート

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