Selenium Dioxide → 2-Ethoxyphenylglyoxal

HRID 66324ノート

反応式

HRID 66324 の反応式
C([O:3][CH2:4][C:5]([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)=[O:6])C.[Se](=O)=O.[O:16]1CCO[CH2:18][CH2:17]1>O.C(OCC)(=O)C>[CH2:17]([O:16][C:12]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[C:5]([CH:4]=[O:3])=[O:6])[CH3:18]

参加物

6

反応物 3

HCID 24007Selenium DioxideHCID 312751,4-DioxaneHCID 1398412-Ethoxy-1-phenylethan-1-one

生成物 1

HCID 227549162-Ethoxyphenylglyoxal

試薬・触媒・溶媒 2

HCID 962Water溶媒HCID 8857Ethyl Acetate溶媒

実験手順

2 g of 2-ethoxyacetophenone are dissolved in 20 ml of dioxane, and a solution of 2 g of selenium dioxide in one ml of water is added thereto. The solution is refluxed for 10 hours. After the reaction, insoluble materials are removed by filtration, and the filtrate is concentrated. The residue thus obtained is dissolved in ethyl acetate. The ethyl acetate solution is washed with water and then with an aqueous sodium bicarbonate solution and water. Then, said solution is dried and evaporated to remove solvent. 2.1 g of 2-ethoxyphenylglyoxal are obtained as a crude oil.

後処理

  1. temperatureThe solution is refluxed for 10 hours
  2. customAfter the reaction, insoluble materials
  3. customare removed by filtration
  4. concentrationthe filtrate is concentrated
  5. customThe residue thus obtained
  6. washThe ethyl acetate solution is washed with water
  7. customis dried
  8. customevaporated
  9. customto remove solvent

出典と根拠

ORDレコード
ord-74c949b65bbb45b78134c4849088b0f2
出典データセット
uspto-grants-1978_12
特許番号
US04131686

反応ノート

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