Acetic Anhydride → 5-(Trifluoromethyl)isobenzofuran-1,3-dione
反応式
[F:1][C:2]([F:16])([F:15])[C:3]1[CH:4]=[C:5]([C:12]([OH:14])=[O:13])[C:6](=[CH:10][CH:11]=1)[C:7](O)=[O:8].C(OC(=O)C)(=O)C>>[F:1][C:2]([F:16])([F:15])[C:3]1[CH:4]=[C:5]2[C:12](=[O:14])[O:13][C:7](=[O:8])[C:6]2=[CH:10][CH:11]=1参加物
3
実験手順
4-Trifluoromethylphthalic acid (106.6 g.) and acetic anhydride (215 cc.) are heated at the reflux temperature for 30 minutes. After concentrating the mixture under reduced pressure (30 mm.Hg), the residue is stirred with cyclohexane (420 cc.). After filtration and drying, 4-trifluoromethylphthalic anhydride (73.5 g.), melting at 54° C., is obtained.
後処理
- concentrationAfter concentrating the mixture under reduced pressure (30 mm.Hg)
- filtrationAfter filtration
- customdrying
出典と根拠
- ORDレコード
- ord-32b5d7c475b04f468a9c379ef539b463
- 出典データセット
- uspto-grants-1978_12
- 特許番号
- US04131674
反応ノート
読み込み中…