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2-(3-Nitrophenyl)oxazolo[4,5-b]pyridine → 3-(Oxazolo[4,5-b]pyridin-2-yl)aniline
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-(3-Nitrophenyl)oxazolo[4,5-b]pyridine | HCID 12461374 | — |
| 触媒 | Palladium | HCID 23938 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 3-(Oxazolo[4,5-b]pyridin-2-yl)aniline | HCID 611086 | — |
反応手順
A mixture of 700mg. of 2-(3-nitrophenyl)oxazolo[4,5-b]pyridine in 50 ml. of ethanol was hydrogenated over 150 mg. of 5% palladium-on-carbon catalyst. The catalyst was removed by filtration and the solvent was concentrated to dryness. The residue was recrystallized from chloroform-petroleum ether to give 2-(3-aminophenyl)oxazolo[4,5-b]pyridine, m.p. 179°-180.5° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04131677 |
| 出典データセット | uspto-grants-1978_12 |
| ORD ID | ord-08c5e003bb1e44bfb83ec6053d9066fd |
| 出典メモ | uspto-grants-1978_12 |