1-(2-Chloroethyl)pyrrolidine hydrochloride → 1-{2-Chloro-4-[2-(N-pyrrolidinyl)ethoxy]-phenyl}-1-butanone

HRID 66609

反応式

HRID 66609 の反応式
[Cl:1][C:2]1[CH:7]=[C:6]([O:8][CH2:9][CH2:10][N:11]([CH2:14][CH3:15])[CH2:12][CH3:13])[CH:5]=[CH:4][C:3]=1[C:16](=[O:20])[CH2:17][CH2:18][CH3:19].Cl.ClCCN1CCCC1>>[Cl:1][C:2]1[CH:7]=[C:6]([O:8][CH2:9][CH2:10][N:11]2[CH2:12][CH2:13][CH2:15][CH2:14]2)[CH:5]=[CH:4][C:3]=1[C:16](=[O:20])[CH2:17][CH2:18][CH3:19]

参加物

3

反応物 2

HCID 816681-(2-Chloroethyl)pyrrolidine hydrochlorideHCID 130523711-[2-Chloro-4-(2-diethylaminoethoxy)phenyl]-1-butanone

生成物 1

HCID 204971661-{2-Chloro-4-[2-(N-pyrrolidinyl)ethoxy]-phenyl}-1-butanone

実験手順

This compound is prepared by essentially the same procedure as described in Example 1 Step A except that the 2-diethylaminoethyl chloride hydrochloride of Example 1 Step A is replaced by an equimolecular quantity of N-(2-chloroethyl)pyrrolidine hydrochloride. The product is obtained as a pale yellow oil upon distillation in vacuo (0.3 mm.).

後処理

  1. customThis compound is prepared by essentially the same procedure
  2. customThe product is obtained as a pale yellow oil upon distillation in vacuo (0.3 mm.)

出典と根拠

ORDレコード
ord-3b2fef9249ba4fb9b8c9f123edf9d8cb
出典データセット
uspto-grants-1982_08
特許番号
US04342782

関連ノート

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