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Sodium Hydroxide → 2-(beta-Hydroxypropylthio)nitrobenzene
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | o-Nitrobenzenethiol | HCID 21002 | — |
| 反応物 | 1-Chloro-2-propanol | HCID 31370 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 2-(beta-Hydroxypropylthio)nitrobenzene | HCID 20530674 | 94.8% |
反応手順
In accordance with Reaction I of Example 1, 15.5 g. (0.1 mole) of 2-nitrothiophenol, 11.34 g. (0.12 mole) of 1-chloro-2-propanol, 4.0 g. (0.1 mole) of sodium hydroxide and 150 ml. of water were used for the reaction and an oily product was extracted with benzene after the reaction and benzene was distilled off after a dehydration to obtain 20.2 g. of blackish brawn liquid 2-(β-hydroxypropylthio)nitrobenzene (yield of 94.8%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04342859 |
| 出典データセット | uspto-grants-1982_08 |
| ORD ID | ord-86835705cda74f718b42990acbcada29 |
| 出典メモ | uspto-grants-1982_08 |