2-Methoxyethanol → Ethanamine, 2-(2-methoxyethoxy)-N,N-bis[2-(2-methoxyethoxy)ethyl]-

HRID 66708

反応式

HRID 66708 の反応式
Cl.Cl[CH2:3][CH2:4][N:5]([CH2:9][CH2:10]Cl)[CH2:6][CH2:7]Cl.[CH3:12][O:13][CH2:14][CH2:15][OH:16]>>[CH2:4]([N:5]([CH2:9][CH2:10][O:16][CH2:15][CH2:14][O:13][CH3:12])[CH2:6][CH2:7][O:16][CH2:15][CH2:14][O:13][CH3:12])[CH2:3][O:16][CH2:15][CH2:14][O:13][CH3:12]

参加物

3

反応物 2

HCID 80192-MethoxyethanolHCID 61220Tris(2-chloroethyl)amine hydrochloride

生成物 1

HCID 112414Ethanamine, 2-(2-methoxyethoxy)-N,N-bis[2-(2-methoxyethoxy)ethyl]-

実験手順

To the mixture thus obtained, 51.6 g of tris(2-chloroethyl)amine hydrochloride (0.215 mole) are added. The mixture is then heated at the reflux temperature of the 2-methoxyethanol (125° C.) for 12 hours and then the solvent is removed by distillation under reduced pressure. The excess sodium 2-methoxyethanolate is neutralized by the addition of 11.6 cm3 aqueous HCl (10 N). The sodium chloride is filtered off and the solution is distilled.

後処理

  1. customTo the mixture thus obtained
  2. customthe solvent is removed by distillation under reduced pressure
  3. additionThe excess sodium 2-methoxyethanolate is neutralized by the addition of 11.6 cm3 aqueous HCl (10 N)
  4. filtrationThe sodium chloride is filtered off
  5. distillationthe solution is distilled

出典と根拠

ORDレコード
ord-37b0d164ffb34296893c305c60f37d3c
出典データセット
uspto-grants-1982_08
特許番号
US04343745

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