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2,2,2-Trichloroethanimidamide → HCID 178516502、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2,2,2-Trichloroethanimidamide | HCID 35608 | — |
| 反応物 | Acetoacetate | HCID 6971017 | — |
| 反応物 | Pyrimidinyl carbamate | HCID 54270844 | — |
| 生成物 | HCID 178516502 | HCID 178516502 | — |
反応手順
The pyrimidinyl carbamate compounds of the present invention may be prepared by reacting trichloroacetamidine with the corresponding acetoacetate to form the corresponding 4-hydroxy-2-trichloromethylpyrimidine, which is then reacted with a selected carbamoyl chloride. These general reactions are illustrated below in equations (A) and (B). In equation (A), trichloroacetamidine is reacted with methylacetoacetate to form 4-hydroxy-6-methyl-2-trichloromethylpyrimidine. In equation (B), the 4-hydroxy-6-methyl-2-trichloromethylpyrimidine is reacted with dimethylcarbamoyl chloride to form 6-methyl-2-trichloromethyl-4-pyrimidinyl dimethylcarbamate. ##STR3##
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04343803 |
| 出典データセット | uspto-grants-1982_08 |
| ORD ID | ord-fa375f70ac0e4887b51c5e9492a4cc48 |
| 出典メモ | uspto-grants-1982_08 |