Potassium Carbonate → HCID 178516067、化合物

HRID 66722

反応式

HRID 66722 の反応式
[Cl:1][C:2]([Cl:7])([Cl:6])[C:3]([NH2:5])=[NH:4].C(=O)([O-])[O-].[K+].[K+].C([O:16][C:17](=O)[CH2:18][C:19]([CH2:21][Cl:22])=O)C>O>[Cl:22][CH2:21][C:19]1[N:5]=[C:3]([C:2]([Cl:7])([Cl:6])[Cl:1])[N:4]=[C:17]([OH:16])[CH:18]=1

参加物

5

反応物 3

HCID 11430Potassium CarbonateHCID 356082,2,2-TrichloroethanimidamideHCID 69484Ethyl 4-chloroacetoacetate

生成物 1

HCID 178516067HCID 178516067、化合物収率 36.1%

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

A mixture of 30.0 g (0.18 mole) trichloroacetamidine, 25.2 g (0.18 mole) potassium carbonate, 30.3 g (0.18 mole) ethyl-4-chloroacetoacetate and 400 ml water was stirred 18 hours. The aqueous solution was filtered and acidified with hydrochloric acid to give a precipitate. The precipitate was washed and dried to give 17.0 g (36% yield) of crude product. An analytical sample recrystallized from ligroin had mp 138°-144° C. The structure was confirmed via infrared and elemental analysis.

後処理

  1. filtrationThe aqueous solution was filtered
  2. customto give a precipitate
  3. washThe precipitate was washed
  4. customdried

出典と根拠

ORDレコード
ord-332f755aa4f94c26b724fcd1f0380f00
出典データセット
uspto-grants-1982_08
特許番号
US04343803

関連ノート

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