化工社化工社 化学情報印刷レポート · 研究参考用
Methanol → 2-Chloro-3-methoxypyrazine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methanol | HCID 887 | — |
| 反応物 | 2,3-Dichloropyrazine | HCID 78575 | — |
| 反応物 | Sodium | HCID 5360545 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 2-Chloro-3-methoxypyrazine | HCID 11804891 | — |
反応手順
A mixture of 0.1 mole of 2,3-dichloropyrazine and 2.3 g. (0.1 mole) of sodium in 160 ml. of anhydrous methanol is refluxed 5-10 hours, and poured into water. The product is extracted with ether or chloroform and recrystallized from a suitable solvent such as ethanol to give pure 2-chloro-3-methoxypyrazine.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04343802 |
| 出典データセット | uspto-grants-1982_08 |
| ORD ID | ord-5d9f55db9a254bf2810c8ee901af2276 |
| 出典メモ | uspto-grants-1982_08 |