化工社化工社 化学情報印刷レポート · 研究参考用
Benzyl Alcohol → 2-Amino-3-morpholino-5-benzyloxypyrazine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzyl Alcohol | HCID 244 | — |
| 反応物 | Sodium hydride | HCID 24758 | — |
| 反応物 | 5-Bromo-3-morpholinopyrazin-2-amine | HCID 16740441 | — |
| 溶媒 | Benzene | HCID 241 | — |
| 生成物 | 2-Amino-3-morpholino-5-benzyloxypyrazine | HCID 20528934 | — |
反応手順
Sodium hydride (0.1 mole) is added to benzyl alcohol (0.1 mole) in 100 ml. dry benzene and the mixture is refluxed one to two hours. The cooled solution is treated with 0.1 mole of 2-amino-3-morpholino-5-bromopyrazine in 100 ml. of benzene and the resulting mixture refluxed for 20-60 hours whereupon it is cooled, washed with water, dried and evaporated to give 2-amino-3-morpholino-5-benzyloxypyrazine.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04343802 |
| 出典データセット | uspto-grants-1982_08 |
| ORD ID | ord-211a8934f2b34af3a63246b2895799df |
| 出典メモ | uspto-grants-1982_08 |