関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | 4-Bromophenylhydrazine hydrochloride | HCID 12157 | — |
| 反応物 | N-(3-oxocyclohexyl)acetamide | HCID 20529251 | — |
| 溶媒 | Acetic Acid | HCID 176 | — |
| 生成物 | N-(6-bromo-1,3,4,9-tetrahydro-2H-carbazol-2-yl)acetamide | HCID 20529232 | — |
反応手順
A solution of 0.05 mol of N-(3-oxocyclohexyl)acetamide in 100 ml of glacial HOAc was stirred and heated at 80° C. while adding during 15-30 minutes a warm solution of 0.05 mol of 4-bromophenylhydrazine hydrochloride in 300 ml of glacial HOAc. After an additional 3 hr at 85°, most of the HOAc was evaporated. The residue was triturated with H2O, until solid, the resulting solid was filtered, and recrystallized from ethanol to give the title compound, mp 210°-211°.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04343812 |
|---|
| 出典データセット | uspto-grants-1982_08 |
|---|
| ORD ID | ord-2bfa85bc87604b8b955eec3ed01d9979 |
|---|
| 出典メモ | uspto-grants-1982_08 |
|---|
