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Acetic Acid → N-(1,3,4,9-tetrahydro-6-methoxy-2H-carbazol-2-yl)acetamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Acetic Acid | HCID 176 | — |
| 反応物 | Sodium Acetate | HCID 517045 | — |
| 反応物 | 4-Methoxyphenylhydrazine hydrochloride | HCID 2723904 | — |
| 反応物 | N-(3-oxocyclohexyl)acetamide | HCID 20529251 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | N-(1,3,4,9-tetrahydro-6-methoxy-2H-carbazol-2-yl)acetamide | HCID 20529230 | — |
反応手順
A mixture of 0.05 mol of N-(3-oxocyclohexyl)acetamide, 0.05 mol of anhydrous NaOAc, 0.05 mol of 4-methoxyphenylhydrazine hydrochloride, and 155 ml of glacial HOAc was stirred for 1 hr at room temperature and then refluxed for 1 hr. The cooled reaction mixture was poured into H2O and the product triturated until solid. Filtration, drying, and recrystallization from ethanol gave the title compound, mp 191°-193°.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04343812 |
| 出典データセット | uspto-grants-1982_08 |
| ORD ID | ord-6a0f5cf8f0194f998e78bfb08f016bef |
| 出典メモ | uspto-grants-1982_08 |