Water → N-(1,3,4,9-tetrahydro-7-methoxy-2H-carbazol-2-yl)acetamide
反応式
O=[C:2]1[CH2:7][CH2:6][CH2:5][CH:4]([NH:8][C:9](=[O:11])[CH3:10])[CH2:3]1.Cl.[CH3:13][O:14][C:15]1[CH:16]=[C:17]([NH:21]N)[CH:18]=[CH:19][CH:20]=1.O>CC(O)=O>[CH3:13][O:14][C:15]1[CH:16]=[C:17]2[C:18]([C:7]3[CH2:6][CH2:5][CH:4]([NH:8][C:9](=[O:11])[CH3:10])[CH2:3][C:2]=3[NH:21]2)=[CH:19][CH:20]=1参加物
5
実験手順
A mixture of 0.05 mol of N-(3-oxocyclohexyl)acetamide and 0.05 mol of 3-methoxyphenylhydrazine hydrochloride in 50 ml of glacial HOAc was stirred for 2 hr at room temperature and then refluxed for 2 hr. The cooled reaction mixture was poured into H2O and the product triturated until solid. Filtration, drying, and recrystallization from ethanol gave the title compound, mp 192°-193°.
後処理
- temperaturerefluxed for 2 hr
- customThe cooled reaction mixture
- customthe product triturated until solid
- filtrationFiltration
- customdrying
- customrecrystallization from ethanol
出典と根拠
- ORDレコード
- ord-26d3e2ada4cb4243a69017519fac37bd
- 出典データセット
- uspto-grants-1982_08
- 特許番号
- US04343812
反応ノート
読み込み中…