Acetic Anhydride → HCID 20529234、化合物

HRID 66793ノート

反応式

HRID 66793 の反応式
[CH3:1][NH:2][CH:3]1[CH2:15][CH2:14][C:13]2[C:12]3[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=3)[NH:6][C:5]=2[CH2:4]1.C(O[C:20](=[O:22])[CH3:21])(=O)C>>[CH2:4]1[C:5]2[NH:6][C:7]3[C:12](=[CH:11][CH:10]=[CH:9][CH:8]=3)[C:13]=2[CH2:14][CH2:15][CH:3]1[N:2]([CH3:1])[C:20](=[O:22])[CH3:21]

参加物

3

反応物 2

HCID 7918Acetic AnhydrideHCID 20529239HCID 20529239、化合物

生成物 1

HCID 20529234HCID 20529234、化合物

実験手順

A mixture of 10.0 g (0.05 mol) of 2,3,4,9-tetrahydro-N-methyl-1H-carbazol-2-amine and 70 ml of acetic anhydride was heated at reflux until complete solution occurred (2-3 min). After standing overnight at room temperature and further cooling at 0°, the precipitated solid was filtered, washed first with small portions of cold acetic anhydride and then thoroughly with anhydrous ether. The crude product was recrystallized from ethanol to give the title compound, mp 215°-216°.

後処理

  1. temperaturewas heated
  2. temperatureat reflux until complete solution
  3. custom(2-3 min)
  4. temperaturefurther cooling at 0°
  5. filtrationthe precipitated solid was filtered
  6. washwashed first with small portions of cold acetic anhydride
  7. customThe crude product was recrystallized from ethanol

出典と根拠

ORDレコード
ord-f260fdb95519483a82452841833e0e24
出典データセット
uspto-grants-1982_08
特許番号
US04343812

反応ノート

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